Pharmacology and Medicinal Chemistry IV

This is the fourth course of the pharmacology series which combines knowledge gained from the three previous courses for the treatment of neuropsychiatric disorders, osteoporosis, reproductive disorders, and Cancer. Students are expected to understand and apply the normal physiology of associated body systems and the pathophysiology of the disease states to interpret drug action mechanisms. This allows an in-depth understanding of how specific drugs treat specific conditions utilizing mechanism-based approaches. The pharmacology and medicinal chemistry of drugs used for the treatment of a disease state are investigated with an integrated approach in explaining the molecular and cellular mechanisms of drug effects on the human body (i.e., pharmacodynamics) as well as how the human body affects the drugs (i.e. pharmacokinetics). Students are expected to gain a deeper understanding of the principles of drug action and should be able to explain and predict outcomes based on the principles of pharmacology, toxicology and medicinal chemistry including pharmacogenomics.