Pharmacology and Medicinal Chemistry II

This is the second course of the pharmacology/ Medicinal Chemistry series which emphasize the pharmacology and medicinal chemistry of drugs used for the treatment of renal disorders, diabetes, hypertension, hyperlipidemia, coagulation disorders, ischemic heart disease, acute coronary syndrome, cardiac arrhythmias, stroke, acute & chronic heart disease, and pulmonary arterial hypertension. In addition, endocrine disorders (thyroid and adrenal/pituitary), Lupus, Osteoarthritis, Rheumatoid Arthritis are also being taught. This course prepares students to develop an in-depth understanding of mechanism-based approaches to how specific drugs are utilized to treat specific conditions. Drug action mechanisms used for the treatment of a disease state are investigated with an integrated approach in explaining the molecular and cellular mechanisms of drug effects on the human body (i.e. pharmacodynamics) as well as how the human body affects the drugs (i.e., pharmacokinetics). Students are expected to gain a deeper understanding of the principles of drug action and should be able to explain and predict outcomes based on the principles of pharmacology, toxicology and medicinal chemistry including pharmacogenomics.